Description

8-(Trifluoromethoxy)Chroman-4-One is a high-purity fluorinated organic building block characterized by its chromanone core and trifluoromethoxy substituent. This compound is valued for its role as a key synthetic intermediate in the development of advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and metabolic stability.
• Material Science: Serves as a precursor for fluorinated polymers, liquid crystals, and other advanced materials requiring specific electronic or surface properties.
• Chemical Synthesis: Employed in organic synthesis for the construction of complex heterocyclic compounds and as a scaffold for library development in medicinal chemistry.

Basic Information

Product Name	8-(Trifluoromethoxy)Chroman-4-One
CAS No.	276697-79-1
Molecular Formula	C10H7F3O3
Molecular Weight	232.16 g/mol
Synonyms	8-(Trifluoromethoxy)-4-chromanone; 4H-1-Benzopyran-4-one, 8-(trifluoromethoxy)-; 8-(Trifluoromethoxy)chroman-4-one; 8-Trifluoromethoxychroman-4-one; 276697-79-1; Chroman-4-one, 8-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our 8-(Trifluoromethoxy)Chroman-4-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.