Description

2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-1,3,4-Oxadiazole is a high-value, heterocyclic boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable synthetic intermediates for drug discovery, ligand synthesis, and the development of organic electronic materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those containing the 1,3,4-oxadiazole pharmacophore.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides that require specific heterocyclic structures.
• Material Science & OLED Development: A crucial precursor for creating organic light-emitting diode (OLED) materials, electron-transport layers, and other functional organic electronic components.
• Ligand & Catalyst Design: Employed in the development of novel ligands for transition metal catalysis and organometallic complexes.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored properties.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new synthetic pathways in chemical research laboratories.

Basic Information

Product Name	2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-1,3,4-Oxadiazole
CAS No.	276694-19-0
Molecular Formula	C₁₄H₁₈BN₃O₃
Molecular Weight	287.12 g/mol
Synonyms	4-(1,3,4-Oxadiazol-2-yl)phenylboronic acid pinacol ester; 2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,3,4-oxadiazole; 4-(1,3,4-Oxadiazol-2-yl)benzeneboronic acid pinacol ester; 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1,3,4-oxadiazole; (4-(1,3,4-Oxadiazol-2-yl)phenyl)boronic acid pinacol ester; PINACOL 4-(1,3,4-OXADIAZOL-2-YL)BENZENEBORONATE
EINECS	Contact for details

Quality Control

Our 2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-1,3,4-Oxadiazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and batch-to-batch consistency suitable for demanding research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Recommended storage temperature: 2-8°C (refrigerated) for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.