Description

4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzohydrazide is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its dual functionality, combining a protected boronic acid group with a reactive hydrazide moiety, enabling its use in Suzuki-Miyaura cross-coupling reactions and as a precursor for heterocyclic synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for drug discovery and advanced material development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing biaryl or heteroaryl structures via Suzuki coupling.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require boronic acid derivatives.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed in the design and synthesis of chemical probes, enzyme inhibitors, and bioconjugation reagents.
• Ligand Synthesis: Acts as a precursor for creating novel bidentate or tridentate ligands used in catalysis.
• Heterocyclic Chemistry: The reactive hydrazide group facilitates the construction of various nitrogen-containing heterocycles like pyrazoles, triazoles, and oxadiazoles.

Basic Information

Product Name	4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzohydrazide
CAS No.	276694-16-7
Molecular Formula	C13H19BN2O3
Molecular Weight	262.11 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid hydrazide; Benzoic acid, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, hydrazide; 4-Pinacolatoboranylbenzohydrazide; (4-Hydrazinylcarbonylphenyl)boronic acid pinacol ester; 4-Boronoic acid, benzoic acid hydrazide, pinacol ester; 4-Carboxyhydrazidephenylboronic acid pinacol ester; 276694-16-7 (CAS); Benzohydrazide, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
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Quality Control

Our 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzohydrazide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, such as pharmaceutical R&D and GMP-compliant production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.