Description

n-Boc-n-Bis(Peg1-Oh) CAS NO 275385-03-0 is a specialized, high-purity chemical intermediate featuring a Boc-protected amine and dual polyethylene glycol (PEG) hydroxyl arms. This compound matters for its role as a versatile building block in the synthesis of complex molecules, offering enhanced solubility and controlled reactivity. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for applications in drug discovery, bioconjugation, and polymer chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, particularly for solubility enhancement.
• Bioconjugation Linker: Used to attach drugs, dyes, or other functional groups to proteins, antibodies, or nanoparticles via its reactive hydroxyl and protected amine sites.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for creating functionalized PEG-based polymers and hydrogels with tailored properties.
• Peptide Synthesis: Employed in solid-phase and solution-phase peptide synthesis to introduce PEG spacers and protected amine functionalities.
• Prodrug Development: Facilitates the design of prodrugs by providing a cleavable linker that improves pharmacokinetics and bioavailability.
• Research & Development: A valuable tool in medicinal chemistry and chemical biology for exploring new molecular entities and their interactions.

Basic Information

Product Name	n-Boc-n-Bis(Peg1-Oh)
CAS No.	275385-03-0
Molecular Formula	C13H27NO6
Molecular Weight	293.36 g/mol
Synonyms	1-Boc-1,1-bis(2-hydroxyethoxy)methylamine; tert-Butyl N,N-bis(2-hydroxyethyl)carbamate; N-Boc-N,N-bis(2-hydroxyethyl)amine; N-(tert-Butoxycarbonyl)-N,N-bis(2-hydroxyethyl)amine; 2,2'-((((tert-Butoxycarbonyl)amino)methylene)bis(oxy))diethanol; Boc-N(CH2CH2OH)2; N-Boc-diethanolamine; 275385-03-0
EINECS	Contact for details

Quality Control

Our n-Boc-n-Bis(Peg1-Oh) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.