Description

2-Pyrrolidinecarbonitrile, 1-(Chloroacetyl)- (9Ci) is a high-purity, specialized organic intermediate of significant interest in advanced chemical synthesis. Its core value lies in its bifunctional molecular structure, which makes it a versatile building block for constructing complex nitrogen-containing heterocycles. This compound is primarily needed by research and development chemists and process scale-up teams within the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel pyrrolidine-based drug candidates, including potential kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific heterocyclic scaffolds for bioactivity.
• Chemical Research & Development: Serves as a versatile building block in organic synthesis for creating complex molecular libraries and exploring new chemical spaces in medicinal chemistry.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services for clients in life sciences.

Basic Information

Product Name	2-Pyrrolidinecarbonitrile, 1-(Chloroacetyl)- (9Ci)
CAS No.	274901-37-0
Molecular Formula	C7H9ClN2O
Molecular Weight	172.61 g/mol
Synonyms	1-(Chloroacetyl)-2-cyanopyrrolidine; 1-(Chloroacetyl)-2-pyrrolidinecarbonitrile; 2-Cyanopyrrolidine, 1-(chloroacetyl)-; 1-Chloroacetyl-2-cyanopyrrolidine; 2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)-; N-(Chloroacetyl)-2-cyanopyrrolidine; Pyrrolidine-2-carbonitrile, 1-(2-chloroacetyl)-
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinecarbonitrile, 1-(Chloroacetyl)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.