Description

2,4-Difluorophenylacetone is a high-purity fluorinated aromatic ketone building block essential for advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce difluorophenyl motifs into their target structures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the difluorophenyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: An effective substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.
• Fine Chemical & Flavor/Fragrance Intermediate: Employed in the multi-step synthesis of specialized fluorinated aroma chemicals and other high-value fine chemicals.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in academic and contract research organizations (CROs).

Basic Information

Product Name	2,4-Difluorophenylacetone
CAS No.	274682-91-6
Molecular Formula	C9H8F2O
Molecular Weight	170.16 g/mol
Synonyms	1-(2,4-Difluorophenyl)propan-2-one; 2,4-Difluorophenylacetone; 2',4'-Difluoropropiophenone; 2-Propanone, 1-(2,4-difluorophenyl)-; 2,4-DFPA; 1-(2,4-Difluorophenyl)-2-propanone; α-Methyl-2,4-difluoroacetophenone
EINECS	Contact for details

Quality Control

Our 2,4-Difluorophenylacetone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.