Description

3-(3-Methyl-1,2,4-Oxadiazol-5-Yl)Benzaldehyde is a high-purity organic building block featuring a benzaldehyde core functionalized with a 3-methyl-1,2,4-oxadiazole heterocycle. This compound is valued for its dual reactivity, offering both an aldehyde group for condensation reactions and a stable, electron-deficient heterocyclic moiety that can modulate the physicochemical properties of target molecules. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-inflammatory agents, and CNS-active compounds.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the oxadiazole ring contributes to biological activity and metabolic stability.
• Material Science Precursor: Serves as a building block for functional organic materials, such as ligands for metal-organic frameworks (MOFs) or monomers for specialty polymers.
• Chemical Biology Probe Development: Utilized in creating tagged molecules or affinity probes for studying biological pathways and target engagement.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and exploratory synthesis in heterocyclic chemistry.

Basic Information

Product Name	3-(3-Methyl-1,2,4-Oxadiazol-5-Yl)Benzaldehyde
CAS No.	273727-50-7
Molecular Formula	C10H8N2O2
Molecular Weight	188.18 g/mol
Synonyms	5-(3-Formylphenyl)-3-methyl-1,2,4-oxadiazole; 3-(3-Methyl-1,2,4-oxadiazol-5-yl)benzaldehyde; Benzaldehyde, 3-(3-methyl-1,2,4-oxadiazol-5-yl)-; 3-Formylphenyl 3-methyl-1,2,4-oxadiazole; 273727-50-7; 3-Methyl-5-(3-formylphenyl)-1,2,4-oxadiazole
EINECS	Contact for details

Quality Control

Our 3-(3-Methyl-1,2,4-Oxadiazol-5-Yl)Benzaldehyde is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with the standards required for GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.