Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxaldehyde, 3-(1-Methylethyl)-, (1S,2R,3R,4R)- (9Ci) is a high-purity, chiral bicyclic aldehyde building block of significant interest in advanced organic synthesis. Its defined stereochemistry and reactive aldehyde group make it a versatile precursor for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced, stereospecific pesticides and herbicides where specific chirality is crucial for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands used in asymmetric catalysis (e.g., hydrogenation, cycloaddition reactions).
• Fragrance and Flavor Chemistry: Potential intermediate for synthesizing complex terpenoid-based aroma molecules due to its bicyclic structure.
• Material Science Research: Building block for novel polymers and dendrimers with specific structural properties.
• Academic and R&D Laboratories: Used in methodological studies and the exploration of new organic reaction pathways involving strained olefin systems.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxaldehyde, 3-(1-Methylethyl)-, (1S,2R,3R,4R)- (9Ci)
CAS No.	271578-36-0
Molecular Formula	C11H16O
Molecular Weight	164.24 g/mol
Synonyms	(1S,2R,3R,4R)-3-Isopropylbicyclo[2.2.1]hept-5-ene-2-carboxaldehyde; (1S,endo)-3-(1-Methylethyl)bicyclo[2.2.1]hept-5-ene-2-carboxaldehyde; 3-Isopropyl-2-norbornene-2-carboxaldehyde (stereospecific); endo-3-Isopropyl-5-norbornene-2-carboxaldehyde; Bicyclo[2.2.1]hept-5-ene-2-carboxaldehyde, 3-(1-methylethyl)-, (1S,2R,3R,4R)-; Chiral Norbornene Aldehyde Derivative
EINECS	Contact for details

Quality Control

Every batch of our chiral aldehydes is produced and tested under a strict quality management system. We employ advanced analytical techniques including chiral HPLC, GC, and NMR to ensure excellent enantiomeric excess (ee) and chemical purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity, the container should be kept tightly sealed after each use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.