Description

5-Indoleboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex indole-containing molecules. It is primarily utilized by pharmaceutical R&D teams, agrochemical scientists, and advanced material researchers for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used to create advanced indole-based fungicides, herbicides, and plant growth regulators with enhanced efficacy.
• Material Science Research: Employed in the development of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs) due to the indole scaffold's electronic properties.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes and enzyme inhibitors.
• Academic & Process Chemistry: A valuable reagent for methodological development in organic synthesis and scale-up process optimization.

Basic Information

Product Name	5-Indoleboronic Acid Pinacol Ester
CAS No.	269410-24-4
Molecular Formula	C15H20BNO2
Molecular Weight	257.14 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole; 1H-Indole-5-boronic acid pinacol ester; 5-Indolylboronic acid pinacol ester; 5-(Pinacolatoboryl)-1H-indole; 5-Indoleboronic Acid, Pinacol Ester; 5-Boronindole Pinacol Ester; PINACOL 5-INDOLYBORONATE
EINECS	Contact for details

Quality Control

Our 5-Indoleboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the original container tightly sealed under an inert atmosphere (argon or nitrogen) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.