Description

2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol is a versatile and high-value boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in its role as a protected phenolic boronic acid, offering enhanced stability and handling characteristics for complex coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), especially those containing biaryl or phenolic motifs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the introduction of a functionalized phenolic group is required.
• Liquid Crystal & OLED Materials: Serves as a building block for creating complex organic molecules used in electronic displays and organic light-emitting diodes due to its planar, conjugated potential.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and dendrimers, where the boronic ester group enables precise molecular assembly and functionalization.
• Chemical Biology & Probe Development: Utilized in creating molecular probes and sensors that leverage boronic acid chemistry for detecting sugars or other diol-containing biomolecules.
• Material Science Research: Acts as a precursor for metal-organic frameworks (MOFs) and other porous materials where its phenolic and boronate functionalities can be incorporated.

Basic Information

Product Name	2-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol
CAS No.	269410-22-2
Molecular Formula	C₁₃H₁₉BO₄
Molecular Weight	250.10 g/mol
Synonyms	4-Hydroxy-3-methoxyphenylboronic acid pinacol ester; 2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; Vanillin pinacol boronic ester; (4-Hydroxy-3-methoxyphenyl)boronic acid pinacol ester; 3-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; 269410-22-2; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methoxyphenol
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance in sensitive coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.