Description

(4-Acetyl-[1,1-Biphenyl]-4-Yl)Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and building block for organic synthesis. This compound is valued for its role in facilitating key carbon-carbon bond-forming reactions, such as the Suzuki-Miyaura cross-coupling, which is fundamental in modern medicinal chemistry and materials science. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug candidates, particularly those containing biphenyl and acetylphenyl motifs.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester reagent for palladium-catalyzed coupling to create biaryl structures, a common scaffold in many active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides that require specific biphenyl-based architectures.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor in the synthesis of organic semiconductors and emissive materials for display and lighting technologies.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis and molecular recognition applications.
• Academic & Industrial R&D: A valuable reagent for methodological development in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	(4-Acetyl-[1,1-Biphenyl]-4-Yl)Boronic Acid Pinacol Ester
CAS No.	269410-19-7
Molecular Formula	C22H27BO3
Molecular Weight	350.26 g/mol
Synonyms	4'-Acetylbiphenyl-4-boronic acid pinacol ester; 4-Acetyl-4'-biphenylboronic acid pinacol ester; [1,1'-Biphenyl]-4-boronic acid, 4'-acetyl-, 1,1-dimethylethyl ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)biphenyl-4'-yl methyl ketone; 4-Acetyl-4'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,1'-biphenyl; (4'-Acetylbiphenyl-4-yl)boronic acid pinacol ester; Pinacol (4'-acetyl-[1,1'-biphenyl]-4-yl)boronate
EINECS	Contact for details

Quality Control

Our (4-Acetyl-[1,1-Biphenyl]-4-Yl)Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Assay	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.