Description

2-(6-Methoxy-2-Naphthalenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 269410-13-1 is a high-purity, advanced pharmaceutical intermediate belonging to the class of naphthalene-based boronic esters. This compound is a critical building block in modern organic synthesis, valued for its role in facilitating efficient carbon-carbon bond formation. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the palladium-catalyzed coupling with aryl halides, enabling the synthesis of biaryl structures prevalent in drug discovery.
• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents targeting various disease pathways.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides that require specific naphthalene-based architectures.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated naphthalene core.
• Ligand and Catalyst Development: Acts as a starting material for creating novel ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme functions.

Basic Information

Product Name	2-(6-Methoxy-2-Naphthalenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	269410-13-1
Molecular Formula	C₁₇H₂₁BO₃
Molecular Weight	284.16 g/mol
Synonyms	6-Methoxy-2-naphthaleneboronic acid pinacol ester; 2-(6-Methoxynaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Methoxy-2-naphthylboronic acid pinacol ester; 2-(6-Methoxy-2-naphthyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Methoxynaphthalene-2-boronic acid pinacol ester; 2-(6-Methoxynaphthalen-2-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; Naphthalene-2-boronic acid, 6-methoxy-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 2-(6-Methoxy-2-Naphthalenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity suitable for sensitive cross-coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.