Description

1-Bromo-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzene CAS NO 269410-06-2 is a high-value organoboron building block, specifically a brominated phenylboronic ester, essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for constructing biaryl and heterobiaryl scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific, complex aromatic structures.
• Material Science & Organic Electronics: Serves as a building block for creating organic light-emitting diodes (OLEDs), semiconductors, and liquid crystal materials.
• Chemical Research & Development: A versatile reagent for academic and industrial research in palladium-catalyzed cross-coupling methodologies.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands and organometallic catalysts.
• Fine Chemical Production: Integral to the multi-step synthesis of complex flavors, fragrances, and specialty chemicals.

Basic Information

Product Name	1-Bromo-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzene
CAS No.	269410-06-2
Molecular Formula	C12H16BBrO2
Molecular Weight	283.97 g/mol
Synonyms	2-Bromophenylboronic acid pinacol ester; (2-Bromophenyl)boronic acid pinacol ester; 2-Bromo-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene; 1-Bromo-2-(pinacolatoboryl)benzene; 2-Bromophenylboronic acid, pinacol ester; 2-Bromobenzene-1-boronic acid pinacol ester; 2-BromophenylBPin; 2-BrC6H4Bpin
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzene is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of research and development, with specifications tailored for pharmaceutical and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent hydrolysis and maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Typical 98-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.