Description

2,4,6-Trimethoxyphenylboronic Acid, Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in its enhanced stability compared to the free boronic acid, making it an ideal reagent for Suzuki-Miyaura cross-coupling reactions under demanding conditions. This high-purity intermediate is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and advanced material science, where precise molecular construction is required.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex drug molecules, particularly in the synthesis of active pharmaceutical ingredients (APIs) containing a trimethoxyphenyl moiety.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and semiconductors.
• Chemical Biology Probes: Utilized to create labeled compounds and probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A reliable starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2,4,6-Trimethoxyphenylboronic Acid, Pinacol Ester
CAS No.	269410-04-0
Molecular Formula	C15H23BO5
Molecular Weight	294.15 g/mol
Synonyms	2,4,6-Trimethoxyphenylboronic Acid Pinacol Ester; 2-(2,4,6-Trimethoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 4,4,5,5-Tetramethyl-2-(2,4,6-trimethoxyphenyl)-1,3,2-dioxaborolane; Trimethoxyphenylboronic Acid Pinacol Ester; Pinacol 2,4,6-Trimethoxyphenylboronate; B-(2,4,6-Trimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2,4,6-Trimethoxyphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.