Description

3-Carboxyphenylboronic Acid Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic chemistry. Its core value lies in providing a stable, reactive handle for Suzuki-Miyaura cross-coupling reactions while protecting the sensitive boronic acid functionality. This compound is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and advanced material science, enabling the precise construction of complex biaryl and heterobiaryl structures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides requiring specific biaryl motifs.
• Material Science Research: Building block for organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis.
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors due to its derivatizable carboxylic acid and protected boronate groups.
• Academic & R&D Laboratories: A versatile reagent for methodological development in organic synthesis and medicinal chemistry.

Basic Information

Product Name	3-Carboxyphenylboronic Acid Pinacol Ester
CAS No.	269409-73-6
Molecular Formula	C14H19BO4
Molecular Weight	262.11 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid; Benzoic acid, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 3-Bpin Benzoic Acid; m-Carboxyphenylboronic Acid Pinacol Ester; 3-Carboxybenzeneboronic Acid Pinacol Ester; (3-Carboxyphenyl)boronic Acid Pinacol Ester; 3-(Bpin)benzoic Acid
EINECS	Contact for details

Quality Control

Every batch of 3-Carboxyphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive applications like pharmaceutical R&D. A detailed Certificate of Analysis (COA), including purity by HPLC, identity confirmation (NMR, IR), and impurity profile, is supplied with each shipment to guarantee consistency and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.