Description

4-Methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid is a high-value, multi-functional boronic ester derivative that serves as a critical synthetic intermediate. Its primary value lies in enabling efficient cross-coupling reactions, most notably the Suzuki-Miyaura reaction, which is fundamental for constructing complex organic frameworks. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise, scalable building blocks for drug discovery, ligand synthesis, and polymer development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for compounds containing biaryl or substituted benzoic acid motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aromatic substitutions.
• Material Science & OLED Development: Serves as a precursor for creating organic light-emitting diode (OLED) materials, liquid crystals, and other functional polymers where controlled aromatic coupling is necessary.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new catalytic processes and synthesizing complex organic molecules.
• Ligand & Catalyst Preparation: Utilized in the synthesis of specialized ligands for transition metal catalysts used in asymmetric synthesis and other advanced catalytic applications.

Basic Information

Product Name	4-Methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid
CAS No.	269409-71-4
Molecular Formula	C14H19BO5
Molecular Weight	278.11 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methoxybenzoic acid; 4-Methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid; Benzoic acid, 4-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 3-Borono-4-methoxybenzoic acid pinacol ester; 4-Methoxy-3-boronobenzoic acid pinacol ester; 3-(Pinacolatoboryl)-4-methoxybenzoic acid; 4-Methoxy-3-(pinacolatoboryl)benzoic acid
EINECS	Contact for details

Quality Control

Every batch of our 4-Methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry to confirm identity and quality. Certificates of Analysis (COA) are available for all shipments, ensuring traceability and compliance with your internal quality standards and research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient humidity. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.