Description

4-Hydroxyphenylboronic Acid Pinacol Ester is a protected boronic acid derivative, a crucial intermediate in modern synthetic organic chemistry and pharmaceutical development. Its primary value lies in its enhanced stability compared to the free boronic acid, making it ideal for handling, storage, and use in sensitive cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-purity building blocks for Suzuki-Miyaura coupling and other catalytic transformations.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting various therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable organoboron reagent for forming carbon-carbon bonds in the presence of palladium catalysts, a cornerstone of modern medicinal chemistry.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Liquid Crystal & OLED Material Development: Acts as a precursor in the creation of complex organic molecules for electronic displays and lighting.
• Polymer & Resin Modification: Employed to introduce functional phenolic and boron-containing groups into polymer backbones to alter material properties.
• Chemical Biology & Proteomics: Utilized as a tool compound or linker in the development of biochemical probes and sensors.

Basic Information

Product Name	4-Hydroxyphenylboronic Acid Pinacol Ester
CAS No.	269409-70-3
Molecular Formula	C12H17BO3
Molecular Weight	220.07 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; (4-Hydroxyphenyl)boronic Acid Pinacol Ester; Pinacol (4-Hydroxyphenyl)boronate; 4-Hydroxybenzeneboronic Acid Pinacol Ester; 2-(4-Hydroxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; B-(4-Hydroxyphenyl)boronic Acid Pinacol Ester; 4-Hydroxy Phenyl BPin
EINECS	Contact for details

Quality Control

Our 4-Hydroxyphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	118-122 °C
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.