Description

3-Bromo-6-Methoxy-2-Pyridinecarboxaldehyde is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromo and aldehyde functional groups on a methoxy-substituted pyridine ring, makes it an indispensable precursor for constructing complex heterocyclic systems. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional dyes due to its electron-deficient aromatic system.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Heterocyclic Library Construction: The reactive aldehyde group is utilized in condensation reactions (e.g., with hydrazines, amines) to generate diverse libraries of fused heterocycles for screening.

Basic Information

Product Name	3-Bromo-6-Methoxy-2-Pyridinecarboxaldehyde
CAS No.	269058-49-3
Molecular Formula	C7H6BrNO2
Molecular Weight	216.03 g/mol
Synonyms	2-Bromo-5-Methoxypyridine-6-carboxaldehyde; 6-Methoxy-3-bromopyridine-2-carboxaldehyde; 3-Bromo-6-methoxypicolinaldehyde; 2-Formyl-3-bromo-6-methoxypyridine; 3-Bromo-6-methoxypyridine-2-carbaldehyde; 269058-49-3; 3-Bromo-6-methoxy-2-pyridinecarbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-6-Methoxy-2-Pyridinecarboxaldehyde is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity, the container should be kept under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and moisture uptake. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.