Description

Ethanone, 2,2,2-Trifluoro-1-(3-Propylphenyl)- (9Ci) is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its unique trifluoroacetyl group attached to a propylbenzene scaffold, offering a strategic combination of lipophilicity and electronic properties that are difficult to achieve with other reagents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, particularly where fluorine substitution is used to modulate bioavailability, metabolic stability, and binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory target areas.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides, where the trifluoromethyl ketone moiety can enhance activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting materials, improving charge transport and stability.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with tailored thermal, optical, or surface properties.
• Complex Ligand Synthesis: Utilized in organometallic chemistry for preparing fluorinated ligands used in catalysis.
• Fluorine-19 NMR Spectroscopy: Can act as a probe or reference compound due to its distinct fluorine signature.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-(3-Propylphenyl)- (9Ci)
CAS No.	268557-42-2
Molecular Formula	C11H11F3O
Molecular Weight	216.20 g/mol
Synonyms	1-(3-Propylphenyl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(3-propylphenyl)ethanone; 3-Propyl-α,α,α-trifluoroacetophenone; α,α,α-Trifluoro-3-propylacetophenone; 2,2,2-Trifluoro-1-(3-propylphenyl)ethan-1-one; 3-Propylphenyl trifluoromethyl ketone; Trifluoro(3-propylphenyl)methanone; 268557-42-2
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-(3-Propylphenyl)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity (typically by GC/HPLC), identity confirmation (by IR, NMR), and impurity profiles are available for every shipment. We support compliance with relevant regulatory frameworks for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Standard Grade)
Purity (GC/HPLC)	≥ 99.0% (High Purity Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.