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(+)-1,1'-Bis((2R,4R)-2,4-Diethylphosphotano)Ferrocene(1,5-Cyclooctadiene)Rhodium (I) Tetrafluoroborate CAS NO 268220-96-8
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CAS No.:268220-96-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(+)-1,1'-Bis((2R,4R)-2,4-Diethylphosphotano)Ferrocene(1,5-Cyclooctadiene)Rhodium (I) Tetrafluoroborate is a high-purity, chiral organometallic complex designed for advanced asymmetric catalysis. This compound is valued for its exceptional enantioselectivity and catalytic efficiency in critical carbon-carbon and carbon-heteroatom bond-forming reactions. It is an essential catalyst precursor for R&D and production chemists in the pharmaceutical, fine chemical, and agrochemical industries, where precise stereochemical control is paramount.
Application
- Asymmetric Hydrogenation: A highly effective catalyst for the enantioselective hydrogenation of prochiral olefins, enamines, and ketones, crucial for producing chiral pharmaceutical intermediates.
- Pharmaceutical Synthesis: Used in the development and manufacturing of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity, such as certain antibiotics, antivirals, and cardiovascular drugs.
- Fine Chemical Production: Enables the synthesis of complex, chiral molecules for fragrances, flavors, and advanced materials with specific stereochemical properties.
- Agrochemical Research: Applied in the creation of enantiomerically pure herbicides, fungicides, and plant growth regulators for enhanced efficacy and environmental safety.
- Academic & Industrial R&D: Serves as a benchmark catalyst in methodological development for new asymmetric transformations in academic laboratories and corporate research centers.
- Process Chemistry Optimization: Employed for scaling up enantioselective catalytic processes from laboratory to pilot plant and commercial production scales.
Basic Information
| Item | Details |
|---|---|
| Product Name | (+)-1,1'-Bis((2R,4R)-2,4-Diethylphosphotano)Ferrocene(1,5-Cyclooctadiene)Rhodium (I) Tetrafluoroborate |
| CAS No. | 268220-96-8 |
| Molecular Formula | Contact for details |
| Molecular Weight | Contact for details |
| Synonyms | (R,R)-Me-DuPhos Rhodium(I) (1,5-Cyclooctadiene) Tetrafluoroborate; [(R,R)-Me-DuPhos)Rh(COD)]BF4; (R,R)-1,2-Bis(2,5-diethylphospholano)benzene(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; Rhodium(I)-(R,R)-Me-DuPhos-COD tetrafluoroborate; (R,R)-Me-DuPhos-Rh(COD)BF4; Chiral Rhodium DuPhos Catalyst; Asymmetric Hydrogenation Catalyst Rh-MeDuPhos |
| EINECS | Contact for details |
Quality Control
Every batch of our (+)-1,1'-Bis((2R,4R)-2,4-Diethylphosphotano)Ferrocene(1,5-Cyclooctadiene)Rhodium (I) Tetrafluoroborate is manufactured and tested under strict quality management systems. We ensure high chiral purity and catalytic activity through advanced analytical techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters is provided with each shipment to guarantee batch-to-batch consistency and performance for your sensitive applications.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent oxidation. The container should be kept in a cool, dry, and well-ventilated place, away from incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | Orange to red-brown crystalline solid or powder |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Enantiomeric Purity | ≥ 99.0% ee |
| Rhodium Content | Contact for details |
| Solubility | Soluble in common organic solvents (DCM, THF, Toluene) |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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