Description

4-tert-Butyl-3-(Hydroxymethyl)-1H-Pyrazol-5-Ol is a versatile pyrazole derivative characterized by its hydroxymethyl and tert-butyl substituents, making it a valuable building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, where its specific molecular framework enables precise chemical modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and inflammation.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, photoactive materials, and polymers with tailored properties.
• Chemical Research & Development: A fundamental building block for exploring new chemical spaces and reaction pathways in academic and industrial R&D laboratories.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects where specific, high-purity intermediates are required for client-specific molecule development.

Basic Information

Item	Details
Product Name	4-tert-Butyl-3-(Hydroxymethyl)-1H-Pyrazol-5-Ol
CAS No.	265643-77-4
Molecular Formula	C8H14N2O2
Molecular Weight	170.21 g/mol
Synonyms	5-Hydroxy-4-tert-butyl-1H-pyrazole-3-methanol; 4-(tert-Butyl)-3-(hydroxymethyl)-1H-pyrazol-5-ol; 3-(Hydroxymethyl)-4-tert-butyl-1H-pyrazol-5-ol; 4-tert-Butyl-5-hydroxy-1H-pyrazole-3-methanol; tert-Butyl hydroxymethyl pyrazolol; Pyrazole derivative 265643-77-4
EINECS	Contact for details

Quality Control

Our 4-tert-Butyl-3-(Hydroxymethyl)-1H-Pyrazol-5-Ol is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most critical synthesis stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.