Description

4-(4,5-Diphenyl-2-Imidazolyl)-Phenylboronic Acid is a specialized boronic acid derivative featuring a conjugated imidazole-phenyl core, making it a valuable building block in advanced organic synthesis. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting kinase inhibition or requiring complex biaryl motifs.
• Agrochemical Synthesis: Used to construct novel active ingredients for crop protection products, leveraging its ability to form carbon-carbon bonds under mild conditions.
• Materials Science Research: Serves as a monomer or building block for creating organic electronic materials, such as OLEDs or conductive polymers, due to its extended π-conjugated system.
• Ligand and Catalyst Development: The imidazole moiety can act as a coordinating site, making it useful for developing novel ligands for transition metal catalysis.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and sensors that utilize boronic acid-diol interactions for detection.
• Academic & R&D: A versatile reagent for methodological development in cross-coupling chemistry and the exploration of new synthetic pathways in university and corporate R&D labs.

Basic Information

Item	Detail
Product Name	4-(4,5-Diphenyl-2-Imidazolyl)-Phenylboronic Acid
CAS No.	264889-14-7
Molecular Formula	C21H17BN2O2
Molecular Weight	340.19 g/mol
Synonyms	4-(4,5-Diphenyl-1H-imidazol-2-yl)phenylboronic acid; [4-(4,5-Diphenyl-1H-imidazol-2-yl)phenyl]boronic acid; 2-(4-Boronophenyl)-4,5-diphenyl-1H-imidazole; 4,5-Diphenyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1H-imidazole (pinacol ester precursor); B-[4-(4,5-Diphenyl-1H-imidazol-2-yl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our 4-(4,5-Diphenyl-2-Imidazolyl)-Phenylboronic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.