Description

1-Vinyl-(cis-1,2-Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl))Cyclohexan-1-Ol is a sophisticated, multi-functional organoboron building block designed for advanced synthetic chemistry. This compound is valued for its unique cis-configured bis-boronic ester functionality, which enables precise and efficient cross-coupling reactions, particularly in the synthesis of complex cyclic and polymer architectures. It is an essential intermediate for R&D and production chemists in the pharmaceutical, agrochemical, and materials science sectors seeking to incorporate boronate ester handles into target molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key monomer or building block for constructing complex organic molecules and polymers via palladium-catalyzed coupling.
• Pharmaceutical Intermediate: Used in the research and development of novel active pharmaceutical ingredients (APIs), especially for creating stereodefined, boron-containing drug candidates.
• Agrochemical Synthesis: Employed in the creation of advanced herbicides, fungicides, and insecticides with tailored properties.
• Functional Material Development: A precursor for organic electronic materials, including OLEDs, OFETs, and conductive polymers, due to its polymerizable vinyl group and boronate esters.
• Chemical Biology & Proteomics: Acts as a versatile probe or linker in bioconjugation strategies and activity-based protein profiling (ABPP).
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	1-Vinyl-(cis-1,2-Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl))Cyclohexan-1-Ol
CAS No.	264144-69-6
Molecular Formula	C22H40B2O5
Molecular Weight	406.17 g/mol
Synonyms	1-Vinyl-1,2-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexanol; cis-1-Vinyl-1,2-bis(pinacolatoboryl)cyclohexanol; 1-Vinyl-1,2-bis(pinacolboronato)cyclohexanol; 1-Vinyl-cis-1,2-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexan-1-ol; 1-Vinyl-1,2-bis(pinacol boronate)cyclohexanol; cis-1,2-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-vinylcyclohexan-1-ol; Cyclohexanol, 1-ethenyl-1,2-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, cis-
EINECS	Contact for details

Quality Control

Our production of 1-Vinyl-(cis-1,2-Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl))Cyclohexan-1-Ol adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) when not in use to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Isomeric Purity (cis-isomer, NMR)	≥ 98.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.