Description

1,3-Benzenedicarboxaldehyde, 5-Ethynyl- (9Ci) is a specialized aromatic dialdehyde building block featuring a strategically positioned ethynyl group. This compound matters as a versatile and reactive intermediate for constructing complex molecular architectures, particularly in advanced materials and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the fields of organic synthesis, medicinal chemistry, and polymer science for applications such as click chemistry, ligand synthesis, and the creation of novel conjugated frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates, leveraging its aldehyde and alkyne functionalities for selective coupling reactions.
• Click Chemistry Reagent: The ethynyl group makes it an ideal participant in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation, polymer functionalization, and material surface modification.
• Ligand and Catalyst Synthesis: Used to construct sophisticated chelating ligands for catalysis and metal-organic frameworks (MOFs), where the dialdehyde can be condensed with amines or hydrazines.
• Polymer and Material Science: Acts as a monomer or cross-linking agent for producing specialty polymers, resins, and advanced materials with tailored optical or electronic properties.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to create complex heterocycles, dendrimers, and other fine chemicals where precise functional group placement is critical.
• Agrochemical Research: Utilized in the development of new crop protection agents and plant growth regulators requiring specific aromatic-aldehyde motifs.

Basic Information

Product Name	1,3-Benzenedicarboxaldehyde, 5-Ethynyl- (9Ci)
CAS No.	263746-70-9
Molecular Formula	C10H6O2
Molecular Weight	158.16 g/mol
Synonyms	5-Ethynylisophthalaldehyde; 5-Ethynylbenzene-1,3-dicarboxaldehyde; 1,3-Diformyl-5-ethynylbenzene; 5-Ethynyl-1,3-benzenedicarboxaldehyde; 5-Ethynylisophthalic aldehyde; Isophthalaldehyde, 5-ethynyl-; 5-Ethynylbenzene-1,3-dialdehyde
EINECS	Contact for details

Quality Control

Our 1,3-Benzenedicarboxaldehyde, 5-Ethynyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.