Description

3-(3-(Trifluoromethyl)Pyridin-2-Yl)Benzaldehyde is a high-value fluorinated aromatic aldehyde building block, essential for advanced organic synthesis. Its molecular structure, featuring a benzaldehyde core linked to a trifluoromethyl-substituted pyridine ring, makes it a critical intermediate for creating compounds with enhanced biological activity and material properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries seeking to incorporate the unique physicochemical characteristics of the trifluoromethyl group into novel molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the CF3 group improves metabolic stability and lipophilicity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands, metal-organic frameworks (MOFs), and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials for OLEDs and semiconductors.
• Chemical Biology Probes: Useful in designing fluorescent tags, photoaffinity labels, and other molecular probes for biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs serving the global life sciences market.

Basic Information

Product Name	3-(3-(Trifluoromethyl)Pyridin-2-Yl)Benzaldehyde
CAS No.	263349-08-2
Molecular Formula	C13H8F3NO
Molecular Weight	251.21 g/mol
Synonyms	2-[3-(Trifluoromethyl)pyridin-2-yl]benzaldehyde; 3-(3-Trifluoromethyl-2-pyridinyl)benzaldehyde; Benzaldehyde, 3-[3-(trifluoromethyl)-2-pyridinyl]-; 263349-08-2; 3-(3-Trifluoromethylpyridin-2-yl)benzaldehyde; 3-(3-(Trifluoromethyl)-2-pyridyl)benzaldehyde
EINECS	Contact for details

Quality Control

Our 3-(3-(Trifluoromethyl)Pyridin-2-Yl)Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to reliable supply and batch-to-batch reproducibility supports your stringent R&D and scale-up requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon) to maintain optimal purity and stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.