Description

Bicyclo[1.1.1]pentane, 1-fluoro-3-(trifluoromethyl)- (9Ci) is a highly fluorinated, strained bicyclic organic compound with the CAS number 262851-98-9. This specialized building block is valued for its unique three-dimensional structure and the introduction of fluorine atoms, which are critical for modulating the physicochemical properties of advanced materials and pharmaceuticals. It is primarily sought by research chemists and process development scientists in the agrochemical, pharmaceutical, and materials science industries for applications in medicinal chemistry, ligand design, and the synthesis of novel fluorinated polymers.

Application

• Pharmaceutical Intermediate: Serves as a key fluorinated scaffold in medicinal chemistry for the development of new drug candidates, potentially enhancing metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the fluorine atoms can improve biological activity and environmental persistence.
• Advanced Materials: Acts as a monomer or precursor for synthesizing specialty fluoropolymers with unique thermal, chemical, or surface properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel, sterically demanding ligands for catalysis.
• Chemical Biology Probes: Useful for incorporating fluorine tags into biomolecules for studies using techniques like 19F NMR spectroscopy.
• Academic and Industrial R&D: A valuable reagent for fundamental research in organic synthesis and fluorine chemistry.

Basic Information

Product Name	Bicyclo[1.1.1]pentane, 1-fluoro-3-(trifluoromethyl)- (9Ci)
CAS No.	262851-98-9
Molecular Formula	C7H6F4
Molecular Weight	166.12 g/mol
Synonyms	1-Fluoro-3-(trifluoromethyl)bicyclo[1.1.1]pentane; 1-Fluoro-3-(trifluoromethyl)-1,3-dihydrodicyclopenta[a,e]pentalene (incorrect but historical); BCP-F-CF3; Fluorinated Bicyclo[1.1.1]pentane Derivative; 3-(Trifluoromethyl)-1-fluorobicyclo[1.1.1]pentane
EINECS	Contact for details

Quality Control

Every batch of Bicyclo[1.1.1]pentane, 1-fluoro-3-(trifluoromethyl)- is produced and analyzed under strict quality protocols. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its classification as a fluoride/strong alkali reactive and highly volatile compound, it should be kept away from heat, sparks, and incompatible materials. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC or HPLC)	≥ 95% (Research Grade)
Purity (GC or HPLC)	≥ 98% (Premium Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.