Description

Neopentylzinc Iodide is a highly reactive organozinc reagent, specifically a dialkylzinc compound, known for its utility in advanced organic synthesis. Its value lies in its ability to act as a potent nucleophile for the efficient transfer of the neopentyl group, enabling the construction of sterically hindered carbon-carbon bonds. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable reagents for complex molecular assembly.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for introducing the bulky neopentyl moiety into drug candidate molecules, potentially improving metabolic stability and bioavailability.
• Agrochemical Active Ingredient Development: Used in the synthesis of novel pesticides and herbicides where specific steric properties are required for target activity.
• Advanced Material Precursor: Employed in the production of specialized polymers, ligands for catalysts, and organic electronic materials.
• Cross-Coupling Reactions: Serves as an efficient organometallic partner in Negishi and related cross-coupling protocols for C-C bond formation.
• Asymmetric Synthesis: Utilized in stereoselective transformations to create chiral centers adjacent to quaternary carbon atoms.
• Organic Methodology Research: A valuable tool for academic and industrial R&D laboratories exploring new synthetic pathways and reaction mechanisms.

Basic Information

Product Name	Neopentylzinc Iodide
CAS No.	262422-94-6
Molecular Formula	C5H11IZn
Molecular Weight	263.44 g/mol
Synonyms	Zinc, iodoneopentyl-; (Neopentyl)zinc iodide; Iodoneopentylzinc; Di-tert-butylzinc iodide (common naming convention); (2,2-Dimethylpropyl)zinc iodide; Neopentyl zinc iodide solution; Organozinc reagent C5; IZnCH2C(CH3)3
EINECS	Contact for details

Quality Control

Our Neopentylzinc Iodide is manufactured and handled under stringent quality systems. Each batch undergoes rigorous analytical testing, including titration for active zinc content and spectroscopic analysis for identity and purity verification, to ensure consistency and reliability for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing assay, solvent content, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being highly volatile, hygroscopic (moisture-sensitive), and easily oxidized (store under inert atmosphere), this reagent must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures of 2-8°C. Keep the container tightly sealed in a cool, dry, well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR)	Conforms to structure
Assay (Zinc content by Titration)	≥ 0.5 M in specified solvent (e.g., THF, Diethyl ether)
Purity (GC or NMR)	≥ 95% (relative)
Solvent	As specified (Typical: Tetrahydrofuran)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.