Description

3-(Trifluoromethyl) Cinnamaldehyde is a high-value fluorinated aromatic aldehyde building block, distinguished by its trifluoromethyl group which imparts unique electronic and lipophilic properties. This compound is essential for synthesizing advanced pharmaceutical intermediates and agrochemicals, where the introduction of fluorine atoms is a key strategy for modulating bioactivity and metabolic stability. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the CF3 group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Functional Polymer Monomer: Incorporated into specialty polymers to improve chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, condensations, and as a precursor for other trifluoromethyl-containing fine chemicals.
• Flavor & Fragrance Research: Acts as an intermediate in the synthesis of complex aromatic compounds for specialty fragrance applications.

Basic Information

Product Name	3-(Trifluoromethyl) Cinnamaldehyde
CAS No.	262268-58-6
Molecular Formula	C10H7F3O
Molecular Weight	200.16 g/mol
Synonyms	3-(Trifluoromethyl)cinnamaldehyde; (E)-3-[3-(Trifluoromethyl)phenyl]prop-2-enal; 3-(Trifluoromethyl)benzylideneacetaldehyde; α,3-Bis(trifluoromethyl)cinnamaldehyde (incorrect but common misnomer); 3-CF3 Cinnamaldehyde; m-Trifluoromethylcinnamaldehyde; (E)-3-(3-(Trifluoromethyl)phenyl)acrylaldehyde
EINECS	Contact for details

Quality Control

Every batch of 3-(Trifluoromethyl) Cinnamaldehyde is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as confirmed by HPLC, GC, NMR, and IR spectroscopy. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider packaging under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.