Description

5-Fluoro-2-Methylbenzylamine is a high-purity, versatile aromatic amine building block of significant importance in advanced organic synthesis. Its value lies in the strategic combination of a reactive primary amine group with fluorine and methyl substituents on the benzene ring, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a critical intermediate for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity, stability, and uptake.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Useful as a derivatization agent or a linker in the synthesis of probes and biochemical tools for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Fluoro-2-Methylbenzylamine
CAS No.	261951-69-3
Molecular Formula	C8H10FN
Molecular Weight	139.17 g/mol
Synonyms	(5-Fluoro-2-methylphenyl)methanamine; 1-(5-Fluoro-2-methylphenyl)methanamine; 2-Methyl-5-fluorobenzylamine; 5-Fluoro-2-methylbenzenemethanamine; α-Amino-5-fluoro-2-methyltoluene; 5-Fluoro-o-tolylmethylamine; 2-Methyl-5-fluorophenylmethylamine; 5-Fluoro-2-methylbenzyl amine
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Methylbenzylamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure it meets the highest standards of purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and relevant industry guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation and light, prolonged exposure to air or light should be avoided. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.