Description

3,5-Bis(Trifluoromethyl)Benzylmethylsulfone is a high-value, multi-functional organosulfur compound characterized by its electron-deficient aromatic system and sulfone moiety. This structure makes it a versatile and critical building block and ligand precursor in advanced chemical synthesis. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the trifluoromethyl groups enhance biological activity and metabolic stability.
• Catalyst & Ligand Development: Serves as a precursor for sophisticated ligands in transition metal catalysis, enabling challenging cross-coupling and asymmetric transformations.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic electronic materials due to its electron-accepting properties.
• Fluorinated Compound Library: An essential building block for creating diverse fluorinated compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	3,5-Bis(Trifluoromethyl)Benzylmethylsulfone
CAS No.	261924-41-8
Molecular Formula	C10H7F6O2S
Molecular Weight	306.22 g/mol
Synonyms	1-[(Methylsulfonyl)methyl]-3,5-bis(trifluoromethyl)benzene; [3,5-Bis(trifluoromethyl)phenyl]methyl methyl sulfone; 3,5-Bis(trifluoromethyl)benzyl methyl sulphone; α-Toluenesulfonic acid, 3,5-bis(trifluoromethyl)-, methyl ester; Methyl [3,5-bis(trifluoromethyl)benzyl] sulfone
EINECS	Contact for details

Quality Control

Our 3,5-Bis(Trifluoromethyl)Benzylmethylsulfone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and scale-up applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.