Description

2,4-Dichloro-5-Fluorobenzyl Bromide is a versatile and high-purity halogenated benzyl bromide building block essential for advanced organic synthesis. Its value lies in its reactive benzyl bromide moiety, which facilitates efficient alkylation and coupling reactions to construct complex molecular architectures. This intermediate is critically needed by R&D and production chemists in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the dichloro-fluorophenyl moiety imparts specific biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals.
• Custom Chemical Synthesis: A critical reagent for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Fluorine Chemistry Studies: Valuable substrate for investigating structure-activity relationships (SAR) in fluorinated aromatic systems.

Basic Information

Product Name	2,4-Dichloro-5-Fluorobenzyl Bromide
CAS No.	261763-27-3
Molecular Formula	C7H4BrCl2F
Molecular Weight	267.92 g/mol
Synonyms	1-(Bromomethyl)-2,4-dichloro-5-fluorobenzene; (2,4-Dichloro-5-fluorophenyl)methyl bromide; 5-Fluoro-2,4-dichlorobenzyl bromide; α-Bromo-2,4-dichloro-5-fluorotoluene; 2,4-Dichloro-5-fluoro-α-bromotoluene; 2,4-Dichloro-5-fluorobenzylbromide; Benzene, 1-(bromomethyl)-2,4-dichloro-5-fluoro-
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-5-Fluorobenzyl Bromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with cGMP, ISO, and other relevant regulatory frameworks for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and light-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.