Description

3-Chloro-2-Fluoro-6-(Trifluoromethyl)Phenylacetonitrile is a high-value, multi-functional aromatic nitrile building block designed for advanced chemical synthesis. Its unique halogenated and trifluoromethylated structure makes it a critical intermediate for creating complex molecules with tailored properties. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients, including herbicides, insecticides, and pharmaceutical candidates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides and insecticides, leveraging the fluorine and trifluoromethyl groups for enhanced bioactivity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, where its aromatic core and halogen atoms contribute to specific material properties.
• Organic Synthesis Reagent: A versatile intermediate for constructing complex aromatic systems via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution.
• Fluorinated Compound Development: Integral for research into new fluorinated compounds, a growing area in medicinal and agrochemical chemistry due to their metabolic stability and lipophilicity.

Basic Information

Product Name	3-Chloro-2-Fluoro-6-(Trifluoromethyl)Phenylacetonitrile
CAS No.	261763-16-0
Molecular Formula	C9H4ClF4N
Molecular Weight	237.58 g/mol
Synonyms	2-(3-Chloro-2-fluoro-6-(trifluoromethyl)phenyl)acetonitrile; (3-Chloro-2-fluoro-6-(trifluoromethyl)phenyl)acetonitrile; 3-Chloro-2-fluoro-α-(trifluoromethyl)benzeneacetonitrile; 261763-16-0; Benzeneacetonitrile, 3-chloro-2-fluoro-α-(trifluoromethyl)-; α-(3-Chloro-2-fluoro-6-(trifluoromethyl)phenyl)acetonitrile
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Fluoro-6-(Trifluoromethyl)Phenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.