Description

3-Chloro-2-Fluoro-5-(Trifluoromethyl)Benzyl Bromide is a high-value, multi-halogenated benzyl bromide derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring chlorine, fluorine, and trifluoromethyl substituents, makes it indispensable for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by R&D and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of monomers and functionalized aromatics for advanced polymers, liquid crystals, and electronic materials.
• Custom Synthesis and Contract Manufacturing: A vital reagent for fine chemical and CDMO (Contract Development and Manufacturing Organization) facilities producing bespoke compounds for clients.

Basic Information

Item	Details
Product Name	3-Chloro-2-Fluoro-5-(Trifluoromethyl)Benzyl Bromide
CAS No.	261763-09-1
Molecular Formula	C8H4BrClF4
Molecular Weight	291.47 g/mol
Synonyms	1-(Bromomethyl)-3-chloro-2-fluoro-5-(trifluoromethyl)benzene; (3-Chloro-2-fluoro-5-(trifluoromethyl)phenyl)methyl bromide; α-Bromo-3-chloro-2-fluoro-5-(trifluoromethyl)toluene; 3-Chloro-2-fluoro-5-trifluoromethylbenzyl bromide; Benzene, 1-(bromomethyl)-3-chloro-2-fluoro-5-(trifluoromethyl)-; 261763-09-1; 3-Chloro-2-fluoro-α-bromo-5-(trifluoromethyl)toluene
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Fluoro-5-(Trifluoromethyl)Benzyl Bromide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.