Description

6-Chloro-2-Fluoro-3-Methylbenzyl Bromide is a high-value, multi-functional halogenated benzyl bromide intermediate. This compound is critical for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical synthesis and agrochemical development. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine and chlorine substituents for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized phosphine ligands or metal-organic frameworks (MOFs) used in asymmetric catalysis.
• Material Science Research: Employed in the creation of advanced polymers, liquid crystals, or organic electronic materials where specific halogenated aromatic units are required.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in contract research and manufacturing organizations (CROs/CMOs).
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems and drug-target interactions.

Basic Information

Item	Details
Product Name	6-Chloro-2-Fluoro-3-Methylbenzyl Bromide
CAS No.	261762-88-3
Molecular Formula	C8H7BrClF
Molecular Weight	237.50 g/mol
Synonyms	1-(Bromomethyl)-6-chloro-2-fluoro-3-methylbenzene; (6-Chloro-2-fluoro-3-methylphenyl)methyl bromide; 2-Fluoro-6-chloro-3-methylbenzyl bromide; α-Bromo-6-chloro-2-fluoro-3-methyltoluene; 3-Methyl-6-chloro-2-fluorobenzyl bromide; 6-Chloro-2-fluoro-m-tolylmethyl bromide; 261762-88-3; Bromo(6-chloro-2-fluoro-3-methylphenyl)methane
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Fluoro-3-Methylbenzyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.