Description

6'-Chloro-2'-Fluoro-3'-Methylacetophenone is a high-purity, synthetically valuable aromatic ketone building block. This compound is essential for the development of advanced pharmaceutical intermediates and fine chemicals, offering precise structural functionality for complex molecular synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material science sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing fluorinated and chlorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides where the specific halogen substitution pattern is critical for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers due to its aromatic backbone and halogen functionalities.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific fluorinated acetophenone derivative.

Basic Information

Product Name	6'-Chloro-2'-Fluoro-3'-Methylacetophenone
CAS No.	261762-78-1
Molecular Formula	C9H8ClFO
Molecular Weight	186.61 g/mol
Synonyms	1-(6-Chloro-2-fluoro-3-methylphenyl)ethan-1-one; 2-Fluoro-6-chloro-3-methylacetophenone; 6-Chloro-2-fluoro-3-methylacetophenone; 2'-Fluoro-6'-chloro-3'-methylacetophenone; 1-Acetyl-6-chloro-2-fluoro-3-methylbenzene; 6-Chloro-2-fluoro-3-methylphenylethanone; 261762-78-1; 6'-Chloro-2'-fluoro-3'-methyl acetophenone
EINECS	Contact for details

Quality Control

Our 6'-Chloro-2'-Fluoro-3'-Methylacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.