Description

Methyl 5-Chlorooctafluoropentanoate is a specialized fluorinated ester building block, recognized for its unique combination of a reactive chlorinated terminus and a perfluorinated backbone. This compound matters as a critical intermediate for introducing fluorinated segments into target molecules, enhancing properties like chemical resistance, thermal stability, and surface activity. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel fluorinated compounds and functional polymers.

Application

• Pharmaceutical Intermediate: Used in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and prodrugs to improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key precursor for creating novel fluorinated pesticides and herbicides with enhanced efficacy and environmental persistence.
• Fluoropolymer Modification: Acts as a monomer or grafting agent to incorporate fluorinated side chains into polymers, improving their oil, water, and chemical resistance.
• Surface Active Agents: Employed in the production of fluorinated surfactants and coatings for exceptional surface tension reduction and durability.
• Liquid Crystal & Electronic Materials: Utilized as a building block for fluorinated components in liquid crystal displays (LCDs) and dielectric materials.
• Organic Synthesis Reagent: Functions as a versatile reagent in nucleophilic substitution and coupling reactions to install fluorinated alkyl groups.

Basic Information

Product Name	Methyl 5-Chlorooctafluoropentanoate
CAS No.	261503-67-7
Molecular Formula	C6H3ClF8O2
Molecular Weight	294.53 g/mol
Synonyms	Methyl 5-chloroperfluoropentanoate; 5-Chlorooctafluoropentanoic Acid Methyl Ester; Methyl 5-Chloro-2,2,3,3,4,4,5,5-octafluoropentanoate; Perfluoropentanoic Acid, 5-Chloro-, Methyl Ester; Methyl 5-Chloroperfluorovalerate; 5-Chloro-2,2,3,3,4,4,5,5-octafluoropentanoic Acid Methyl Ester; Methyl 5-Chloro-1,1,2,2,3,3,4,4-octafluoropentanoate; Methyl 5-Chloro-2,2,3,3,4,4,5,5-octafluoropentanoate
EINECS	Contact for details

Quality Control

Our Methyl 5-Chlorooctafluoropentanoate undergoes rigorous quality testing to ensure compliance with industry standards for high-purity intermediates. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to strict in-process controls and analytical methods, including GC, HPLC, and NMR, to guarantee consistent quality and supply reliability for your critical synthesis workflows. Certificates are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use and stored away from heat sources and open flames. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.6 g/mL
Boiling Point	Contact for details
Refractive Index (n20/D)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.