Description

(4-Chloro-2-Formyl-Phenyl)-Carbamic Acid tert-Butyl Ester is a high-purity, versatile chemical intermediate of significant importance in advanced organic synthesis. Its core value lies in its bifunctional structure, featuring both a protected amine and an aldehyde group, which makes it a critical building block for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring a specific chlorinated benzaldehyde scaffold with a protected amine handle.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where its structural motifs can impart specific biological activity.
• Organic Synthesis Building Block: Serves as a versatile starting material for palladium-catalyzed cross-coupling reactions, reductive amination, and other transformations to create diverse chemical libraries.
• Material Science Precursor: Potential use in the synthesis of specialized polymers, ligands for catalysis, or organic electronic materials due to its reactive functional groups.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	(4-Chloro-2-Formyl-Phenyl)-Carbamic Acid tert-Butyl Ester
CAS No.	260559-52-2
Molecular Formula	C₁₃H₁₆ClNO₃
Molecular Weight	269.72 g/mol
Synonyms	tert-Butyl N-(4-chloro-2-formylphenyl)carbamate; 4-Chloro-2-formylphenylcarbamic Acid 1,1-Dimethylethyl Ester; BOC-4-Chloro-2-formylaniline; N-Boc-4-chloro-2-aminobenzaldehyde; N-(tert-Butoxycarbonyl)-4-chloro-2-aminobenzaldehyde; 2-(tert-Butoxycarbonylamino)-5-chlorobenzaldehyde; 5-Chloro-2-[(tert-butoxycarbonyl)amino]benzaldehyde
EINECS	Contact for details

Quality Control

Our (4-Chloro-2-Formyl-Phenyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.