Description

1-[4-(Trifluoromethoxy)Phenyl]-1H-Pyrrole-2-Carbaldehyde is a high-value, multi-functional aromatic aldehyde building block featuring a pyrrole core and a trifluoromethoxy substituent. This compound is critical for advanced organic synthesis, where its unique structure enables the development of novel molecules with tailored electronic and steric properties. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group can enhance biological activity and metabolic stability.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: A versatile building block for constructing complex heterocyclic systems via reactions such as condensation, cyclization, and cross-coupling.
• Ligand & Catalyst Development: Employed in the design and synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	1-[4-(Trifluoromethoxy)Phenyl]-1H-Pyrrole-2-Carbaldehyde
CAS No.	260442-97-5
Molecular Formula	C12H8F3NO2
Molecular Weight	255.20 g/mol
Synonyms	1-[4-(Trifluoromethoxy)phenyl]-1H-pyrrole-2-carboxaldehyde; 1H-Pyrrole-2-carboxaldehyde, 1-[4-(trifluoromethoxy)phenyl]-; 1-(4-Trifluoromethoxyphenyl)-1H-pyrrole-2-carbaldehyde; 2-Formyl-1-[4-(trifluoromethoxy)phenyl]pyrrole; 260442-97-5
EINECS	Contact for details

Quality Control

Our production of 1-[4-(Trifluoromethoxy)Phenyl]-1H-Pyrrole-2-Carbaldehyde adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) against established internal specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.