Description

Tetrahydrofuran-3-Boronic Acid is a versatile heterocyclic boronic acid building block essential for modern synthetic chemistry. Its value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecular architectures. This compound is particularly critical for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for drug discovery, catalyst development, and specialty polymer synthesis.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing functionalized tetrahydrofuran motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science: Employed in the synthesis of organic electronic materials, such as monomers for conductive polymers and components for OLEDs.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and bioconjugates for studying biological processes.
• Academic & Industrial R&D: A fundamental reagent for method development and exploring new synthetic pathways in organic chemistry laboratories worldwide.

Basic Information

Product Name	Tetrahydrofuran-3-Boronic Acid
CAS No.	260369-10-6
Molecular Formula	C4H9BO3
Molecular Weight	115.92 g/mol
Synonyms	3-Tetrahydrofuranylboronic Acid; (Oxolan-3-yl)boronic Acid; THF-3-Boronic Acid; 3-Boronotetrahydrofuran; Tetrahydro-3-furanboronic Acid; 3-THF Boronic Acid; 3-Tetrahydrofurylboronic Acid; Tetrahydrofuran-3-ylboronic Acid
EINECS	Contact for details

Quality Control

Our Tetrahydrofuran-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C, ¹¹B), HPLC for purity assessment, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for sensitive coupling reactions. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.