Description

3-[3-(Trifluoromethoxy)Phenyl]Isoxazole is a high-value fluorinated heterocyclic building block used in advanced organic synthesis. This compound is critical for medicinal chemistry and agrochemical research, enabling the introduction of the trifluoromethoxy-phenyl-isoxazole pharmacophore to modulate biological activity and physicochemical properties. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and crop protection industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in CNS, anti-inflammatory, and antiviral research.
• Agrochemical Active Ingredient Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group enhances lipophilicity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, contributing unique electronic and steric properties.
• Chemical Biology Probe Development: Utilized in crafting molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthesis projects requiring fluorinated isoxazole motifs.

Basic Information

Product Name	3-[3-(Trifluoromethoxy)Phenyl]Isoxazole
CAS No.	260046-96-6
Molecular Formula	C10H6F3NO2
Molecular Weight	229.16 g/mol
Synonyms	3-[3-(Trifluoromethoxy)phenyl]-1,2-oxazole; 3-(3-Trifluoromethoxyphenyl)isoxazole; 1,2-Oxazole, 3-[3-(trifluoromethoxy)phenyl]-; α-(Trifluoromethoxy)-m-isoxazolylbenzene; 3-(3-(Trifluoromethoxy)phenyl)isoxazole; Isoxazole, 3-[3-(trifluoromethoxy)phenyl]-; m-(Trifluoromethoxy)phenyl isoxazole
EINECS	Contact for details

Quality Control

Every batch of 3-[3-(Trifluoromethoxy)Phenyl]Isoxazole is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and GC-MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.