Description

3-Aminomethylphenylacetic Acid Ethyl Ester is a versatile pharmaceutical intermediate and fine chemical building block. Its bifunctional structure, featuring both an amine and an ester group, makes it a valuable synthon for constructing complex molecules in medicinal chemistry. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Peptidomimetic Synthesis: Used to incorporate phenylglycine-like structures into peptide analogs to enhance stability and bioavailability.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Employed in the creation of chiral ligands for asymmetric synthesis and metal-organic frameworks (MOFs).
• Organic Synthesis Reagent: Functional intermediate for amide coupling reactions, ester hydrolysis/transformation, and the introduction of aminomethyl aromatic motifs.
• Bioconjugation Chemistry: Useful linker molecule for attaching fluorescent probes, drugs, or other functionalities to biomolecules.

Basic Information

Product Name	3-Aminomethylphenylacetic Acid Ethyl Ester
CAS No.	259818-63-8
Molecular Formula	C12H17NO2
Molecular Weight	207.27 g/mol
Synonyms	Ethyl 2-(3-(Aminomethyl)phenyl)acetate; 2-[3-(Aminomethyl)phenyl]acetic Acid Ethyl Ester; 3-(Aminomethyl)benzeneacetic Acid Ethyl Ester; Ethyl (3-Aminomethyl)phenylacetate; m-(Aminomethyl)phenylacetic Acid Ethyl Ester; 3-Carbamidomethylphenylacetic Acid Ethyl Ester (common misnomer); Benzeneacetic acid, 3-(aminomethyl)-, ethyl ester; A key intermediate for certain GABA derivatives.
EINECS	Contact for details

Quality Control

Our 3-Aminomethylphenylacetic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption and potential degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.