Description

1-(4-Bromo-2-Fluorophenyl)Propan-1-One is a high-purity, versatile aromatic ketone building block essential for advanced organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the bromo-fluoro-phenyl group acts as a core structural element.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) precursors or liquid crystals.
• Custom Chemical Synthesis: A valuable scaffold for contract research organizations (CROs) and custom synthesis houses building bespoke compounds for client projects.
• Academic Research: Used in university and institutional labs for methodological studies in cross-coupling reactions and fluorination chemistry.

Basic Information

Product Name	1-(4-Bromo-2-Fluorophenyl)Propan-1-One
CAS No.	259750-61-3
Molecular Formula	C9H8BrFO
Molecular Weight	231.06 g/mol
Synonyms	4'-Bromo-2'-fluoropropiophenone; 1-Propanone, 1-(4-bromo-2-fluorophenyl)-; 4-Bromo-2-fluoropropiophenone; p-Bromo-o-fluoropropiophenone; 1-(4-Bromo-2-fluorophenyl)-1-propanone; 2-Fluoro-4-bromopropiophenone; 4-Bromo-2-fluoro-1-propiophenone; 259750-61-3
EINECS	Contact for details

Quality Control

Every batch of 1-(4-Bromo-2-Fluorophenyl)Propan-1-One is manufactured and tested under a strict quality management system. We guarantee high chemical purity and consistency, supported by comprehensive analytical documentation. A detailed Certificate of Analysis (COA) providing results for identity, assay, and impurity profiles is supplied with each shipment to ensure it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider using an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.