Description

1-[5-[2-(Trifluoromethoxy)Phenyl]-2-Furyl]Ethan-1-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique furan and trifluoromethoxy-substituted phenyl structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific fluorine-containing motifs. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of target drug molecules, especially those with fluorinated aromatic systems.
• Agrochemical Research: Serves as a structural component in the development of new pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and stability.
• Material Science: Used in research for creating specialized organic ligands or monomers for advanced polymers and functional materials.
• Chemical Synthesis: Acts as a versatile reagent for constructing complex heterocyclic frameworks in academic and industrial organic chemistry laboratories.
• Life Science Research: Employed in biochemical and pharmacological studies as a probe or standard compound to investigate structure-activity relationships (SAR).

Basic Information

Product Name	1-[5-[2-(Trifluoromethoxy)Phenyl]-2-Furyl]Ethan-1-One
CAS No.	259251-82-6
Molecular Formula	C13H9F3O3
Molecular Weight	270.21 g/mol
Synonyms	1-[5-[2-(Trifluoromethoxy)phenyl]-2-furanyl]ethanone; 2'-Trifluoromethoxy-2-acetylfuran; 1-(5-(2-(Trifluoromethoxy)phenyl)furan-2-yl)ethan-1-one; Ethanone, 1-[5-[2-(trifluoromethoxy)phenyl]-2-furanyl]-; CAS 259251-82-6
EINECS	Contact for details

Quality Control

Our 1-[5-[2-(Trifluoromethoxy)Phenyl]-2-Furyl]Ethan-1-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP-oriented synthesis and research requiring traceable, high-quality intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.