Description

Boronic Acid, (2-Hydroxy-3,4-Dimethylphenyl)- (9Ci) is a specialized organoboron compound featuring a phenolic hydroxyl group adjacent to the boronic acid functionality. This unique bifunctional structure makes it a valuable building block in organic synthesis, particularly for the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for constructing complex molecular architectures, including potential active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those requiring biaryl or heterobiaryl linkages.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical boron-containing coupling partner for palladium-catalyzed reactions with organic halides.
• Ligand Synthesis: Used in the development of novel ligands for catalysis, leveraging both the boronic acid and phenolic groups for coordination.
• Material Science Research: Employed in the creation of organic frameworks, polymers, and functionalized surfaces.
• Chemical Biology Probes: Utilized for labeling or modifying biomolecules due to its selective reactivity.
• Agrochemical Synthesis: Intermediate in the development of new crop protection agents with complex aromatic structures.

Basic Information

Product Name	Boronic Acid, (2-Hydroxy-3,4-Dimethylphenyl)- (9Ci)
CAS No.	259209-31-9
Molecular Formula	C9H13BO3
Molecular Weight	180.01 g/mol
Synonyms	(2-Hydroxy-3,4-dimethylphenyl)boronic acid; 3,4-Dimethyl-2-hydroxybenzeneboronic acid; 2-Hydroxy-3,4-dimethylbenzeneboronic acid; (3,4-Dimethyl-2-hydroxyphenyl)boronic acid; Boronic acid, B-(3,4-dimethyl-2-hydroxyphenyl)-; 259209-31-9; B-(3,4-Dimethyl-2-hydroxyphenyl)boronic acid
EINECS	Contact for details

Quality Control

Our Boronic Acid, (2-Hydroxy-3,4-Dimethylphenyl)- (9Ci) is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing including HPLC for purity and NMR for structural confirmation to ensure it meets high-grade specifications for research and synthesis. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to minimize moisture uptake and preserve stability. Recommended storage temperature is 2-8°C for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.