Description

3-(5-(2-Trifluoromethoxyphenyl)2-Furyl)Propenoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique furan and propenoic acid structure substituted with a trifluoromethoxy group. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. Pharmaceutical R&D departments, agrochemical innovators, and specialty chemical manufacturers need this material to develop next-generation compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the trifluoromethoxy group for improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a sophisticated organic ligand or precursor in catalytic systems for asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique optical or electronic properties.
• Bioconjugation and Probe Chemistry: Utilized in the design of molecular probes and diagnostic agents due to its reactive propenoic acid moiety.
• Academic and Industrial R&D: A valuable tool compound for medicinal chemistry programs and structure-activity relationship (SAR) studies.

Basic Information

Product Name	3-(5-(2-Trifluoromethoxyphenyl)2-Furyl)Propenoic Acid
CAS No.	259196-57-1
Molecular Formula	C₁₄H₉F₃O₄
Molecular Weight	298.22 g/mol
Synonyms	(E)-3-[5-[2-(Trifluoromethoxy)phenyl]-2-furyl]acrylic acid; 3-[5-[2-(Trifluoromethoxy)phenyl]furan-2-yl]prop-2-enoic acid; 2-Propenoic acid, 3-[5-[2-(trifluoromethoxy)phenyl]-2-furanyl]-; 3-(5-(2-Trifluoromethoxyphenyl)furan-2-yl)acrylic acid; 259196-57-1; TFMP-Furan-Acrylic Acid
EINECS	Contact for details

Quality Control

Our 3-(5-(2-Trifluoromethoxyphenyl)2-Furyl)Propenoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and heavy metals. We provide comprehensive Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.