Description

5-[2-Chloro-5-(Trifluoromethyl)Phenyl]Furfural is a high-value, multi-functional aromatic furan derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in synthetic organic chemistry. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and fungicides, leveraging its unique halogenated trifluoromethylphenyl moiety.
• Material Science Research: Acts as a precursor for specialty polymers and liquid crystals due to its rigid furan core and electron-withdrawing groups.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and as a aldehyde component in condensation reactions to create novel heterocyclic compounds.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in regulatory submissions.

Basic Information

Item	Detail
Product Name	5-[2-Chloro-5-(Trifluoromethyl)Phenyl]Furfural
CAS No.	259196-40-2
Molecular Formula	C12H6ClF3O2
Molecular Weight	274.62 g/mol
Synonyms	5-(2-Chloro-α,α,α-trifluoro-p-tolyl)furfural; 2-Chloro-5-(trifluoromethyl)benzene-1-carbaldehyde; 5-[2-Chloro-5-(trifluoromethyl)phenyl]-2-furaldehyde; 2-Chloro-α,α,α-trifluoro-5-furfurylbenzaldehyde; (2-Chloro-5-(trifluoromethyl)phenyl)furan-5-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 5-[2-Chloro-5-(Trifluoromethyl)Phenyl]Furfural is manufactured under a strict quality management system. We provide comprehensive analytical documentation to ensure traceability and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, and NMR are available upon request and are essential for regulatory and R&D purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.