Description

Ethanone, 2,2,2-Trifluoro-1-Imidazo[5,1-B]Thiazol-7-Yl- (9Ci) is a specialized trifluoromethylated heterocyclic ketone, a high-value building block in advanced organic synthesis. This compound is critical for introducing the imidazothiazole pharmacophore and the metabolically stable trifluoroacetyl group into target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in antiviral, antibacterial, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, leveraging the biological activity of the imidazothiazole core.
• Material Science Precursor: Serves as a building block for specialty polymers and advanced organic electronic materials requiring specific heterocyclic architectures.
• Fluorine Chemistry: An essential reagent for introducing the trifluoromethyl ketone moiety, a crucial functional group in medicinal chemistry for modulating lipophilicity and metabolic stability.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-Imidazo[5,1-B]Thiazol-7-Yl- (9Ci)
CAS No.	258839-25-7
Molecular Formula	C7H3F3N2OS
Molecular Weight	220.17 g/mol
Synonyms	2,2,2-Trifluoro-1-(imidazo[5,1-b]thiazol-7-yl)ethanone; 7-Trifluoroacetyl-imidazo[5,1-b]thiazole; 1-(Imidazo[5,1-b][1,3]thiazol-7-yl)-2,2,2-trifluoroethanone; 258839-25-7; Trifluoroacetyl imidazothiazole; TFIT; Imidazo[5,1-b]thiazol-7-yl trifluoromethyl ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-Imidazo[5,1-B]Thiazol-7-Yl- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and MS confirmation. A Certificate of Analysis (COA) detailing all specifications is supplied with each batch to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.