Description

1-(4-Trifluoromethylphenyl)Butane-1,3-Dione is a specialized diketone compound featuring a trifluoromethylphenyl group, which imparts unique electronic and steric properties. This compound is a valuable high-purity chemical intermediate for advanced synthesis, particularly in the development of pharmaceuticals and agrochemicals where the trifluoromethyl group is a key pharmacophore. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the CF3 group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for β-diketone ligands used in coordination chemistry and catalysis for organic transformations.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient aromatic system.
• Chemical Research: A versatile reagent for heterocyclic synthesis, including pyrazoles, isoxazoles, and other nitrogen-containing rings.
• Fluorine Chemistry Studies: An important compound for investigating structure-activity relationships (SAR) in fluorinated organic molecules.

Basic Information

Product Name	1-(4-Trifluoromethylphenyl)Butane-1,3-Dione
CAS No.	258346-69-9
Molecular Formula	C11H9F3O2
Molecular Weight	230.18 g/mol
Synonyms	4,4,4-Trifluoro-1-[4-(trifluoromethyl)phenyl]butane-1,3-dione; 1-(4-Trifluoromethylphenyl)-1,3-butanedione; 4,4,4-Trifluoro-1-(4-trifluoromethylphenyl)butane-1,3-dione; 4'-(Trifluoromethyl)phenyl-1,3-butanedione; 1,3-Butanedione, 1-[4-(trifluoromethyl)phenyl]-; 4,4,4-Trifluoro-1-(alpha,alpha,α-trifluoro-p-tolyl)-1,3-butanedione
EINECS	Contact for details

Quality Control

Our 1-(4-Trifluoromethylphenyl)Butane-1,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.