Description

(4-Boronobenzoyl)Glycine is a specialized boronic acid derivative that serves as a crucial synthetic intermediate in modern organic and medicinal chemistry. Its core value lies in its bifunctional structure, combining a reactive boronic acid group with a glycine moiety, making it a versatile building block for Suzuki-Miyaura cross-coupling reactions and peptide modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, especially in oncology and metabolic disease research.
• Suzuki-Miyaura Cross-Coupling Reagent: Used as a boronic acid component to form carbon-carbon bonds in complex molecule assembly.
• Peptide Modification & Conjugation: Facilitates the site-specific introduction of boron-containing groups into peptides and proteins for bioconjugation.
• Agrochemical Synthesis: Intermediate in the development of new herbicides and plant growth regulators with targeted modes of action.
• Material Science Research: Used in the synthesis of boron-doped organic frameworks and polymers for electronic or sensing applications.
• Chemical Biology Probes: Serves as a precursor for creating probes that study enzyme activity or cellular processes involving carboxylic acid recognition.

Basic Information

Product Name	(4-Boronobenzoyl)Glycine
CAS No.	256656-73-2
Molecular Formula	C9H10BNO4
Molecular Weight	206.99 g/mol
Synonyms	4-Carbamoylmethylcarbonylphenylboronic Acid; Glycine, N-(4-boronobenzoyl)-; p-Boronobenzoylglycine; (4-Boronobenzoyl)aminoacetic Acid; Bz-Gly-B(OH)2; 4-(Glycylcarbonyl)phenylboronic Acid; N-(4-Boronobenzoyl)glycine; 4-Boronobenzoic Acid Glycine Amide
EINECS	Contact for details

Quality Control

Our (4-Boronobenzoyl)Glycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and elemental analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements. Specifications are designed to meet the high standards of pharmaceutical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term storage to maintain stability and purity. Avoid exposure to moisture and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.