Description

Naphthalene-2-Boronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for advanced organic synthesis. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common structural motif in pharmaceuticals and organic electronics.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel drug candidates, particularly those containing naphthalene or extended aromatic systems.
• Agrochemical Research: Employed in creating new active ingredients for crop protection products requiring specific aromatic frameworks.
• Material Science: A precursor for organic light-emitting diodes (OLEDs), liquid crystals, and other advanced organic materials where controlled conjugation is needed.
• Chemical Biology & Proteomics: Can be utilized in the synthesis of molecular probes and tags for studying biological systems.
• Catalyst & Ligand Development: Serves as a starting material for synthesizing novel ligands used in homogeneous catalysis.

Basic Information

Product Name	Naphthalene-2-Boronic Acid, Pinacol Ester
CAS No.	256652-04-7
Molecular Formula	C₁₆H₂₁BO₂
Molecular Weight	256.15 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalene; 2-Naphthylboronic Acid Pinacol Ester; Naphthalen-2-yl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(Naphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-Naphthaleneboronic Acid Pinacol Ester; Pinacol 2-Naphthylboronate; 2-NaphthylBPin; 2-Naphthalenylboronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our Naphthalene-2-Boronic Acid, Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.